Key result
Hypertensive patients had a greater brachial to digital systolic pressure gradient than normotensive controls during both heating and cooling, with no significant difference in diastolic gradients.
Why the study?
Does the brachial to digital blood pressure gradient differ between normal subjects and patients with essential hypertension under varying states of peripheral vasomotor tone?
Population
16 subjects, comprising 10 patients with essential hypertension and 6 subjects with normal blood pressure
Comparison
Regulated peripheral vasoconstriction and… vs Subjects with normal blood pressure
Design
Cross-sectional
Authors
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May reflect hypertension-related vascular changes independent of tone; hypothesis-generating and should not yet change practice.
Observational (n=16)
Does the brachial to digital blood pressure gradient differ between normal subjects and patients with essential hypertension under varying states of peripheral vasomotor tone?
Patients with essential hypertension exhibit a greater brachial to digital systolic blood pressure gradient compared to normotensive individuals, regardless of peripheral vasomotor tone.
Gaskell et al. (1958) conducted an observational in Essential hypertension (n=16). Essential hypertension vs. Normal blood pressure was evaluated on Brachial to digital systolic and diastolic pressure gradients. Hypertensive patients had a greater brachial to digital systolic pressure gradient than normotensive controls during both heating and cooling, with no significant difference in diastolic gradients.