Key result
VATS lobectomy in the early postoperative PCI period for patients with NSCLC and severe CHD resulted in no perioperative deaths and 2 cases of postoperative atrial fibrillation among 14 patients.
Why the study?
Does VATS lobectomy in the early postoperative PCI period control perioperative hemorrhage and cardiovascular risks in patients with NSCLC and severe CHD?
Observational (n=14)
No
Does VATS lobectomy in the early postoperative PCI period control perioperative hemorrhage and cardiovascular risks in patients with NSCLC and severe CHD?
VATS lobectomy performed in the early post-PCI period appears feasible for patients with NSCLC and severe CHD, allowing for timely cancer resection with acceptable perioperative cardiovascular risk.
BACKGROUND: In recent years, based on clinical observations, the number of lung cancer patients with concomitant coronary heart disease (CHD) has gradually increased. However, because of the requirement of long-term anticoagulant therapy after percutaneous coronary intervention (PCI), some of these patients lose the opportunity for surgical treatment, resulting in tumor progression. The objective of this study was to determine the appropriate timing of video-assisted thoracic surgery (VATS) lobectomy after PCI without increasing perioperative cardiovascular risk. METHODS: This study retrospectively analyzed clinical data of patients with a combination of NSCLC and CHD who underwent selective pulmonary lobectomy by VATS in the early postoperative PCI period between 2010 and 2015 at Beijing Chaoyang Hospital, China. RESULTS: Fourteen patients received VATS lobectomy after PCI. The disease had progressed to T stage in two patients after PCI. No perioperative death occurred. Two patients suffered postoperative atrial fibrillation: one had a pulmonary infection, and the other had acute coronary syndrome. All patients recovered and were discharged. CONCLUSION: For NSCLC patients with severe CHD, the use of VATS lobectomy in the early postoperative PCI period could not only advance the timing of surgery, but may also control perioperative hemorrhage and CHD event risks within acceptable ranges, which could provide more patients with an opportunity to undergo surgical treatment.
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Li et al. (2017) conducted an observational in Non-small cell lung cancer (NSCLC) and concomitant coronary heart disease (CHD) (n=14). VATS lobectomy in the early postoperative PCI period was evaluated on Perioperative death and complications. VATS lobectomy in the early postoperative PCI period for patients with NSCLC and severe CHD resulted in no perioperative deaths and 2 cases of postoperative atrial fibrillation among 14 patients.
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