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NSAIDs may continue for post-orthopaedic analgesia; challenges rodent-based restrictions and leaves open need for human bone-healing trials.
EDITOR —We cannot let Varghese et al's letter go unchallenged. After extrapolation of rodent data they say that non-steroidal anti-inflammatory drugs should not be used after orthopaedic surgery.1 Prompted by similar views from some of our surgical colleagues, we recently undertook a comprehensive electronic literature search of the effects of non-steroidal anti-inflammatory drugs in orthopaedics, trauma, and bone metabolism. We also …
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Stone et al. (1998) studied this question.
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