Key result
Continuation of antithrombotic therapy during interventional pain procedures was associated with lower intraoperative local bleeding (69.5% vs 75.4%) but higher intravascular penetration (13.0% vs 10.9%) compared to discontinuation, with no major hemorrhagic complications observed.
Why the study?
Does continuing antithrombotic therapy increase bleeding complications in patients undergoing interventional pain management techniques compared to discontinuation?
Population
3,179 patients undergoing interventional pain management techniques in a private practice specialty referral…
Comparison
Continuation of antithrombotic therapy during… vs Discontinuation of antithrombotic therapy prior…
Design
Cohort
Follow-up
postoperative period
Authors
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May support antithrombotic continuation without major bleeding in pain procedures; hypothesis-generating and should not change practice pending RCTs.
Observational (n=3,179)
No
Does continuing antithrombotic therapy increase bleeding complications in patients undergoing interventional pain management techniques compared to discontinuation?
Absolute Event Rate: 69.5% vs 75.4%
p-value: p=<0.05
Continuing aspirin and clopidogrel during interventional pain procedures does not significantly increase major bleeding complications compared to discontinuation.
Laxmaiah Manchikanti (2011) conducted an observational in Chronic pain (n=3,179). Antithrombotic therapy continuation vs. Antithrombotic therapy discontinuation was evaluated on Intraoperative local bleeding (p=<0.05). Continuation of antithrombotic therapy during interventional pain procedures was associated with lower intraoperative local bleeding (69.5% vs 75.4%) but higher intravascular penetration (13.0% vs 10.9%) compared to discontinuation, with no major hemorrhagic complications observed.
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