Key result
Electrical pacing at 1 Hz evoked tachycardia-like excitation in isolated rat atria, initiated by the coupling of spontaneous and evoked action potentials that generated a linear blocked area.
In an isolated rat atrium model, electrical pacing at 1 Hz evokes tachycardia-like excitation via the coupling of spontaneous and evoked action potentials.
Findings in isolated rat atria do not support clinical practice changes; hypothesis-generating for reentry mechanisms in atrial arrhythmias.
Multiple-site optical recording of membrane potential activity using a voltage-sensitive dye was employed to monitor action potentials in the rat atrium. Electrical pacing at 1 Hz evoked the events of tachycardia-like excitation (TE). Optical mapping revealed that a coupling of spontaneous and evoked action potentials resulted in the initiation of TE.
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Tetsuro Sakai (2004) studied Atrial arrhythmia (Tachycardia-like excitation). Electrical pacing was evaluated on Conduction patterns of the excitatory wave during tachycardia-like excitation. Electrical pacing at 1 Hz evoked tachycardia-like excitation in isolated rat atria, initiated by the coupling of spontaneous and evoked action potentials that generated a linear blocked area.
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