Key result
Transcutaneous oximetry monitoring during the early phase of exercise successfully distinguished symptomatic patients with minimal peripheral artery disease from healthy controls.
Why the study?
Does transcutaneous oximetry monitoring during early exercise distinguish patients with early-stage peripheral artery disease from healthy controls?
Case-Control (n=28)
Does transcutaneous oximetry monitoring during early exercise distinguish patients with early-stage peripheral artery disease from healthy controls?
Transcutaneous oximetry during early exercise can effectively distinguish patients with early-stage, minimally symptomatic peripheral artery disease from healthy individuals.
May aid noninvasive early PAD detection; hypothesis-generating and requires prospective validation before clinical adoption.
The present work was performed to test the sensitivity of transcutaneous oximetry in evaluating the first stage of peripheral artery disease in patients with few symptoms. Eighteen nondiabetic patients, stage II according to Fontaine and classified according to their walking capability and Doppler examination, were investigated. Ten healthy subjects served as controls. Measurements were performed with the subjects standing and during exercise on a treadmill. Postischemic hyperemia was also evaluated with strain-guage plethysmography. Standing values did not discriminate between patients and controls; on the contrary the pattern of the early phase of trancutaneous oximetry curves obtained during exercise allowed the investigators to distinguish the symptomatic patients with minimal symptoms. Accuracy and sensitivity of the method further increased when regional perfusion index was considered.
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Modesti et al. (1990) conducted a case-control in Peripheral artery disease (n=28). Transcutaneous oximetry monitoring during exercise vs. Healthy controls was evaluated on Discrimination between patients and controls. Transcutaneous oximetry monitoring during the early phase of exercise successfully distinguished symptomatic patients with minimal peripheral artery disease from healthy controls.
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