Key result
Severe proximal coronary arterial stenosis decreased total septal artery inflow by 52% (P<0.05) and increased systolic retrograde flow by 75% (P<0.05) in dogs.
Why the study?
Does coronary stenosis alter the phasic pattern of septal artery blood flow velocity in dogs?
Population
8 anesthetized open-chest dogs
Comparison
Moderate and severe proximal coronary arterial… vs Control conditions (no stenosis, N)
Design
Preclinical
Authors
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Increases retrograde septal flow in canine stenosis; hypothesis-generating for human coronary hemodynamics.
Does coronary stenosis alter the phasic pattern of septal artery blood flow velocity in dogs?
p-value: p=<0.05
Severe coronary stenosis significantly decreases total and diastolic anterograde flow while increasing systolic retrograde flow in the septal artery of dogs.
Kimura et al. (1992) studied Coronary stenosis (n=8). Coronary stenosis (moderate and severe) vs. No stenosis (control) was evaluated on Septal arterial blood velocity area (total inflow) (p=<0.05). Severe proximal coronary arterial stenosis decreased total septal artery inflow by 52% (P<0.05) and increased systolic retrograde flow by 75% (P<0.05) in dogs.
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