Key result
Generic valsartan (Tantordio) demonstrated comparable antihypertensive efficacy to original valsartan, reducing systolic blood pressure by 25% and diastolic blood pressure by 20%.
Why the study?
Does generic valsartan provide equivalent antihypertensive efficacy and metabolic effects compared to original valsartan in patients with arterial hypertension?
RCT (n=60)
Open-label
Randomized into 2 groups
Yes
Does generic valsartan provide equivalent antihypertensive efficacy and metabolic effects compared to original valsartan in patients with arterial hypertension?
Generic valsartan is clinically equivalent to original valsartan in terms of blood pressure reduction, metabolic effects, and improvements in quality of life and erectile function.
Supports generic substitution for cost savings in hypertension; reinforces RCT evidence of therapeutic equivalence to branded valsartan.
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Мычка et al. (2015) conducted an RCT in Arterial hypertension (n=60). Generic valsartan (Tantordio) vs. Original valsartan was evaluated on Reduction in systolic blood pressure. Generic valsartan (Tantordio) demonstrated comparable antihypertensive efficacy to original valsartan, reducing systolic blood pressure by 25% and diastolic blood pressure by 20%.
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