Key result
Patients with repaired tetralogy of Fallot had significantly lower maximal oxygen consumption compared to healthy controls (38.2 vs 48.1 ml/kg/min, P<0.001).
Why the study?
Do patients with repaired tetralogy of Fallot have reduced maximal exercise capacity compared to healthy controls, and is it related to lung function and pulmonary regurgitation?
Population
34 patients with repaired tetralogy of Fallot repaired 10.0 +/- 4.9 years previously, and 34 healthy matched…
Design
Case-control
Authors
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Reduced exercise capacity warrants attention in repaired tetralogy of Fallot; leaves open contributions from lung function and regurgitation.
Case-Control (n=68)
Do patients with repaired tetralogy of Fallot have reduced maximal exercise capacity compared to healthy controls, and is it related to lung function and pulmonary regurgitation?
Absolute Event Rate: 38.2% vs 48.1%
p-value: p=< 0.001
Impaired exercise capacity in patients with repaired tetralogy of Fallot is partly driven by reduced resting lung function, pulmonary regurgitation, and low ventilatory anaerobic threshold.
Norgård et al. (1992) conducted a case-control in Repaired tetralogy of Fallot (n=68). Repaired tetralogy of Fallot vs. Healthy matched controls was evaluated on Maximal oxygen consumption (p=< 0.001). Patients with repaired tetralogy of Fallot had significantly lower maximal oxygen consumption compared to healthy controls (38.2 vs 48.1 ml/kg/min, P<0.001).
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