Key result
Doppler echocardiography had a diagnostic accuracy of 79% for predicting elevated left ventricular diastolic pressure, comparing favorably to BNP (70%) and chest radiography (61%).
Why the study?
Does Doppler echocardiography improve diagnostic accuracy for determining elevated left ventricular diastolic pressure compared to chest radiography, BNP, and chest auscultation in patients undergoing cardiac catheterization?
Cross-Sectional (n=56)
Does Doppler echocardiography improve diagnostic accuracy for determining elevated left ventricular diastolic pressure compared to chest radiography, BNP, and chest auscultation in patients undergoing cardiac catheterization?
Doppler echocardiography provides better diagnostic accuracy (79%) than BNP, chest radiography, and physical examination for noninvasively predicting elevated left ventricular diastolic pressure.
Answers are grounded in this paper and cite their sources.
Supports Doppler echocardiography for noninvasive LV diastolic pressure assessment; hypothesis-generating and requires prospective validation.
BACKGROUND: Doppler echocardiography (DE), chest radiography (CXR), serum B-type natriuretic peptide (BNP) measurement and physical examination are all commonly employed to estimate left ventricular diastolic pressure (LVDP) in clinical care. There are no published studies directly comparing the diagnostic accuracy of these tests. METHODS AND RESULTS: DE, BNP, CXR, and physical examination were performed on 56 consecutive patients immediately following clinically indicated cardiac catheterization with measurement of LVDP. LVDP measured preceding atrial contraction at end-expiration was elevated (>16 mmHg) in 19 subjects. Diagnostic accuracies were 79%, 70%, 61% for DE, BNP, and CXR, respectively. None of the study subjects had evidence of raised LVDP by chest auscultation. CONCLUSIONS: The diagnostic accuracy of DE compares favorably to other noninvasive markers for prediction of invasively determined LVDP.
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Spevack et al. (2008) conducted a cross-sectional in Patients undergoing clinically indicated cardiac catheterization (n=56). Doppler echocardiography vs. Chest radiography, serum B-type natriuretic peptide, and chest auscultation was evaluated on Diagnostic accuracy for elevated left ventricular diastolic pressure (>16 mmHg). Doppler echocardiography had a diagnostic accuracy of 79% for predicting elevated left ventricular diastolic pressure, comparing favorably to BNP (70%) and chest radiography (61%).
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