Key result
CT angiography was found to be a superior modality compared to Ultrasound Color Doppler for quantifying carotid artery stenosis, whereas Ultrasound Color Doppler was better for characterizing plaque ulceration.
Why the study?
Extracranial carotid atherosclerosis is a leading cause of ischemic stroke, but the comparative effectiveness of MDCTA versus USCD for detection, characterization, and quantification of carotid artery disease required assessment.
Does CT Angiography improve the detection, characterization, and quantification of carotid artery disease compared to Ultrasound Color Doppler in patients with suspected atherosclerotic disease?
Cross-Sectional (n=50)
Single-blind
No
Does CT Angiography improve the detection, characterization, and quantification of carotid artery disease compared to Ultrasound Color Doppler in patients with suspected atherosclerotic disease?
While USCD is a cost-effective first-line screening tool, CTA provides superior quantification of carotid artery stenosis and detailed plaque evaluation.
May support complementary CTA-USCD use for carotid stenosis; leaves open prospective outcome validation before practice change.
Introduction: Stroke is the third most common cause of death in developed word.About 80% strokes are ischemic in nature.Extracranial carotid artery atherosclerosis is third leading cause of ischemic stroke in general population.CT Angiography (MDCTA) and Ultrasound color doppler (USCD) are two frequently employed modalities for evaluation of carotid artery disease.The purpose of this study was to assess effectiveness of CTA compare to USCD in detection, characterization and quantification of carotid artery disease.Material and Methods: Study was conducted in GCS Medical college on fifty patients.MDCTA was performed in patients in which carotid Doppler ultrasound was suggestive of >50% stenosis and high-risk plaque such as ulcerated plaque, irregular surface plaque.Results: Our study shows that CTA angiography is better modality compare to USCD in quantification of stenosis and plaque characterization.Conclusion: USCD should be first line investigation for carotid artery disease.However due to less sensitivity of USCD in determining stenosis and some plaque characteristics CTA should be performed for detailed plaque evaluation.
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Patel et al. (2019) conducted a cross-sectional in Carotid Artery Disease (n=50). CT Angiography (MDCTA) vs. Ultrasound Color Doppler (USCD) was evaluated on Detection, characterization, and quantification of carotid artery stenosis and plaque morphology. CT angiography was found to be a superior modality compared to Ultrasound Color Doppler for quantifying carotid artery stenosis, whereas Ultrasound Color Doppler was better for characterizing plaque ulceration.
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