Key result
Serum omentin levels were positively associated with insulin sensitivity and HDL cholesterol, and inversely associated with BMI and triglycerides (all P≤0.03), which was mediated by adiponectin.
Population
1092 participants of the German KORA F4 survey (2006-2008)
Design
Cross-sectional
Authors
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Omentin-adiponectin axis may mark insulin sensitivity; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=1,092)
p-value: p=≤0.03
In a large population-based cohort, circulating omentin levels were associated with insulin sensitivity, an effect that appears to be mediated by adiponectin.
Herder et al. (2015) conducted a cross-sectional in Abnormal glucose tolerance and related metabolic factors (n=1,092). Serum omentin levels was evaluated on Glucose tolerance and diabetes-related factors (insulin sensitivity, lipids) (p=≤0.03). Serum omentin levels were positively associated with insulin sensitivity and HDL cholesterol, and inversely associated with BMI and triglycerides (all P≤0.03), which was mediated by adiponectin.
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