Key result
Liver samples contained HCV 5' UTR variants not found in serum in 4 of 6 patients with chronic hepatitis.
Why the study?
Are there differences between HCV 5' UTR quasispecies in serum and liver in patients with chronic hepatitis?
Population
n=6 patients with chronic hepatitis
Design
Other
Authors
Loading...
May indicate compartment-specific HCV quasispecies; hypothesis-generating for differential replication and monitoring in chronic hepatitis.
Observational (n=6)
Are there differences between HCV 5' UTR quasispecies in serum and liver in patients with chronic hepatitis?
HCV variants differing in the 5' UTR may be present in the same individual in liver versus serum, possibly replicating with different kinetics.
Jang et al. (1999) conducted an observational in Chronic hepatitis C (n=6). Liver samples vs. Serum samples was evaluated on HCV 5' UTR sequence variants. Liver samples contained HCV 5' UTR variants not found in serum in 4 of 6 patients with chronic hepatitis.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: