Key result
In anesthetized pigs, the intramyocardial blood volume-to-flow relationship was described by rho = AF + B√F, with coefficients changing consistently with increasing microsphere embolization.
Population
Anesthetized pigs (in situ heart of intact experimental animals)
Design
Preclinical
Authors
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Supports CT-based microvascular recruitment modeling in ischemia; leaves open human translation and clinical validation.
In vivo CT imaging can characterize the functional behavior of recruitable and nonrecruitable components of the intramyocardial microvasculature using blood volume-to-flow relationships.
Liu et al. (1995) studied this question. Sequential injections of nonradioactive microspheres was evaluated on Functional behavior of recruitable and nonrecruitable components of the intramyocardial microvasculature (rho-to-F relationship). In anesthetized pigs, the intramyocardial blood volume-to-flow relationship was described by rho = AF + B√F, with coefficients changing consistently with increasing microsphere embolization.
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