Why the study?
How do obesity and cardiorespiratory fitness relate to markers of arterial function such as endothelial vasodilator function and arterial compliance?
Population
53 volunteers, comprising obese and lean subjects.
Design
Cross-sectional
Key result
Obesity was associated with lower endothelial vasodilatator function compared to lean subjects (3.2% vs 5.7%; P<.01), while low cardiorespiratory fitness correlated with reduced arterial compliance.
Authors
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May warrant targeted vascular assessment in obesity; leaves open distinct fitness effects on compliance.
Cross-Sectional (n=53)
How do obesity and cardiorespiratory fitness relate to markers of arterial function such as endothelial vasodilator function and arterial compliance?
Absolute Event Rate: 3.2% vs 5.7%
p-value: p=<.01
Obesity impairs endothelial function (FMD), whereas low cardiorespiratory fitness is associated with reduced large artery compliance, indicating distinct influences on blood vessel health.
Davison et al. (2010) conducted a cross-sectional in Obesity (n=53). Obesity vs. Lean subjects was evaluated on Endothelial vasodilatator function (FMD) (p=<.01). Obesity was associated with lower endothelial vasodilatator function compared to lean subjects (3.2% vs 5.7%; P<.01), while low cardiorespiratory fitness correlated with reduced arterial compliance.