Why the study?
Obesity is associated with increased HF risk, but whether this risk is modulated by improved cardiorespiratory fitness remained to be assessed.
Does increased cardiorespiratory fitness reduce the incidence of heart failure across different body mass index categories in male veterans?
Does increased cardiorespiratory fitness reduce the incidence of heart failure across different body mass index categories in male veterans?
Increased cardiorespiratory fitness is associated with a progressively lower risk of incident heart failure regardless of BMI, suggesting fitness can modulate the HF risk associated with obesity.
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Fitness may attenuate obesity-related HF risk; leaves open whether interventions improve outcomes across BMI.
Kokkinos et al. (2019) studied this question.
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