May 1, 2016European Journal of Heart FailureOpen Access

Tipping the Scales Toward Fitness as a Key Modifier of the Obesity Paradox in Heart Failure

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Why the study?

Does cardiorespiratory fitness explain the obesity paradox regarding mortality in patients with systolic heart failure?

Structured PICO

Does cardiorespiratory fitness explain the obesity paradox regarding mortality in patients with systolic heart failure?

Population

4,623 persons with systolic heart failure from the MECKI Score Research Group (excluding 220 individuals with severe obesity ≥35 kg/m2)

Intervention

Higher cardiorespiratory fitness (predicted peak VO2) and BMI

Comparator

Lower cardiorespiratory fitness and BMI

Outcome

All-cause and cardiovascular mortalityhard clinical

Discussion

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Implication

Cardiorespiratory fitness modifies the obesity paradox in heart failure, indicating that fitness level rather than BMI alone drives the observed survival benefit.

Cite This Study

Adrienne L. Clark (2016) studied this question.

synapsesocial.com/papers/6a855a2637bcb8373dad9a45 https://doi.org/10.1002/ejhf.545

Topics

Heart failure HFrEF treatment HFpEF management

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Implication

Cardiorespiratory fitness modifies the obesity paradox in heart failure, indicating that fitness level rather than BMI alone drives the observed survival benefit.

Tipping the Scales Toward Fitness as a Key Modifier of the Obesity Paradox in Heart Failure

Structured PICO

Discussion

Implication

Cite This Study

Topics

Tipping the Scales Toward Fitness as a Key Modifier of the Obesity Paradox in Heart Failure

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider