Key result
Low cardiorespiratory fitness was associated with a higher risk of heart failure mortality compared to high fitness (HR 3.97, P<0.0001 for trend) in men without baseline cardiovascular disease.
Why the study?
Does higher cardiorespiratory fitness reduce heart failure mortality in men without prior cardiovascular disease?
Cohort (n=44,674)
Does higher cardiorespiratory fitness reduce heart failure mortality in men without prior cardiovascular disease?
Effect estimate: HR 3.97
p-value: p=<0.0001
Higher baseline cardiorespiratory fitness is associated with a significantly lower risk of heart failure mortality in men, independent of BMI and other risk factors.
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May identify low-fitness men for prevention; leaves open whether improving fitness reduces HF mortality.
Farrell et al. (2013) conducted a cohort in No history of cardiovascular disease (n=44,674). Cardiorespiratory fitness (CRF) vs. Low cardiorespiratory fitness was evaluated on Heart failure mortality (HR 3.97, p=<0.0001). Low cardiorespiratory fitness was associated with a higher risk of heart failure mortality compared to high fitness (HR 3.97, P<0.0001 for trend) in men without baseline cardiovascular disease.
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