Why the study?
Conduction system pacing has been used as an alternative for pacemaker-indicated patients requiring ventricular pacing, but real-world safety and performance data were needed.
Does LBBAP improve safety and electrical performance compared to HBP in patients requiring ventricular pacing?
Population
2342 patients undergoing pacemaker implantation for HBP or LBBAP with a Medtronic Model 3830 lead
Comparison
LBBAP vs HBP
Design
Multicenter observational registry analysis
Key result
Left bundle branch area pacing (LBBAP) had a 2.5% lead complication rate at 36 months compared to 6.3% for His-bundle pacing (HBP), along with lower pacing thresholds (P<0.001).
Authors
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LBBAP may reduce lead issues versus HBP; Level 4 data leave superiority open pending randomized trials.
Observational (n=2,342)
Yes
Does LBBAP improve safety and electrical performance compared to HBP in patients requiring ventricular pacing?
Absolute Event Rate: 2.5% vs 6.3%
In a real-world registry, LBBAP was associated with lower lead complication rates and better electrical parameters compared to HBP over 3 years.
Vijayaraman et al. (2024) conducted an observational in Pacemaker indication requiring ventricular pacing (n=2,342). Left bundle branch area pacing (LBBAP) vs. His-bundle pacing (HBP) was evaluated on Lead-related complications at 36 months. Left bundle branch area pacing (LBBAP) had a 2.5% lead complication rate at 36 months compared to 6.3% for His-bundle pacing (HBP), along with lower pacing thresholds (P<0.001).
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