Key result
Maternally acquired anti-CMV IgG disappears before 8 months of age, and 76.7% of primary CMV infections in Chinese children occur between 1 and 3.5 months of age, leading to an overall seroprevalence of 82.4%.
Population
112 mother-newborn pairs (singleton full-term newborns) and 837 healthy children aged 0-8 years in China.
Design
Cohort
Follow-up
up to 24 months
Authors
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Highlights need for early CMV vigilance in Chinese infants; leaves open optimal prevention approaches pending interventional trials.
Observational (n=949)
Yes
Maternally acquired anti-CMV IgG disappears by 8 months of age, and primary CMV infection in Chinese children predominantly occurs very early in life (1-3.5 months).
Chen et al. (2012) conducted an observational in Cytomegalovirus (CMV) infection (n=949). Cytomegalovirus (CMV) exposure was evaluated on Overall seroprevalence of anti-CMV IgG in children aged 0-8 years. Maternally acquired anti-CMV IgG disappears before 8 months of age, and 76.7% of primary CMV infections in Chinese children occur between 1 and 3.5 months of age, leading to an overall seroprevalence of 82.4%.
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