Key result
Among Korean women of childbearing age, overall CMV IgG seropositivity was 95.8%, but was significantly lower at 77.5% in women aged 15 to under 20 years.
Why the study?
The study aimed to investigate the seroprevalence of CMV infection using CMV IgG and IgM antibodies in Korean women of childbearing age.
Cross-Sectional (n=6,837)
No
p-value: p=<0.05
CMV seropositivity is high among Korean women of childbearing age, but significantly lower in those under 20, suggesting a need for prenatal education in this younger group.
Seroprevalence estimates in Korean women of childbearing age support local surveillance; leaves open impact on congenital CMV prevention.
BACKGROUND: The aim of this study was to investigate the seroprevalence of cytomegalovirus (CMV) infection using the serologic status of CMV IgG and IgM antibodies in Korean women of childbearing age. METHODS: We retrospectively reviewed CMV IgG and IgM test results from Korean women aged 15-49 years who underwent testing between January 2009 and December 2019. Seroprevalence of CMV IgG and IgM by year and age was investigated. RESULTS: The study period was 11 years, and among 6837 samples tested, 95.8% were CMV IgG-positive. The seropositivity in women aged 15- <20 years was significantly lower (77.5%) than older age groups. Among 6837 total CMV IgG tests, 75.9% (5186) had concurrently measured CMV IgM results among which 2.4% were IgM-positive. CONCLUSION: Considering the low CMV seropositivity of women younger than 20 years, they may need prenatal education for CMV infection.
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Choi et al. (2021) conducted a cross-sectional in Cytomegalovirus (CMV) infection (n=6,837). Age 15 to <20 years vs. Older age groups was evaluated on CMV IgG seropositivity (p=<0.05). Among Korean women of childbearing age, overall CMV IgG seropositivity was 95.8%, but was significantly lower at 77.5% in women aged 15 to under 20 years.
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