Key result
Hospital treatment with ACE inhibitors or ARBs, beta-blockers, and statins was significantly associated with lower in-hospital mortality among patients with STEMI.
Why the study?
Does hospital treatment with guideline-directed medical therapy and reperfusion therapy reduce in-hospital mortality in patients with STEMI?
Observational (n=25,682)
Yes
Does hospital treatment with guideline-directed medical therapy and reperfusion therapy reduce in-hospital mortality in patients with STEMI?
p-value: p=<0.0001
In-hospital ACEI/ARB, β-blocker, and statin therapy was associated with lower STEMI mortality; leaves open reperfusion timing effects in observational registries.
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Posnenkova et al. (2014) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=25,682). Hospital treatment with ACE-Is or ARBs, beta-blockers, and statins vs. Lack of hospital treatment with these medications was evaluated on In-hospital mortality (p=<0.0001). Hospital treatment with ACE inhibitors or ARBs, beta-blockers, and statins was significantly associated with lower in-hospital mortality among patients with STEMI.
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