Key result
Physical activity, dyspnoea, and chest pain improved significantly 2 years after coronary artery bypass grafting irrespective of preoperative left ventricular ejection fraction.
Why the study?
Does preoperative LVEF influence the improvement of physical activity, dyspnoea, and chest pain 2 years after CABG?
Cohort (n=985)
Does preoperative LVEF influence the improvement of physical activity, dyspnoea, and chest pain 2 years after CABG?
CABG significantly improves patient-reported physical activity, dyspnoea, and chest pain at 2 years regardless of the patient's preoperative left ventricular ejection fraction.
Improvements in activity and symptoms after CABG appear independent of preoperative LVEF; hypothesis-generating and requires randomized confirmation.
To investigate the relationships between limitation of physical activity and dyspnoea and chest pain before and 2 years after coronary artery bypass grafting (CABG) and preoperative left ventricular ejection fraction (LVEF), questionnaires were issued to all patients from Western Sweden who underwent CABG during 1988-1991. The analysis comprised 985 patients. Physical activity improved significantly after CABG regardless of the preoperative LVEF. No significant association was found between LVEF and degree of limitation of physical activity before or after surgery. Dyspnoea and chest pain improved markedly, irrespective of LVEF. There was significant association between freedom from dyspnoea and LVEF preoperatively (less dyspnoea with higher LVEF), but not after CABG. The frequency of chest-pain attacks was not related to LVEF, before or after the operation. Thus physical activity, dyspnoea and chest pain improved in the 2 years after CABG irrespective of preoperative LVEF. Absence of dyspnoea was related to LVEF before, but not after surgery, and there was no association between preoperative LVEF and frequency of anginal attacks before or after CABG.
No takes yet. Share an insight, caveat, or question.
Johan Herlitz (2000) conducted a cohort in Coronary Artery Bypass Grafting (CABG) (n=985). Preoperative left ventricular ejection fraction (LVEF) was evaluated on Limitation of physical activity, dyspnoea and chest pain. Physical activity, dyspnoea, and chest pain improved significantly 2 years after coronary artery bypass grafting irrespective of preoperative left ventricular ejection fraction.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: