What question did this study set out to answer?

To determine the population-level incidence and demographic characteristics of femur fractures with and without atypical features defined by ASBMR criteria.

January 24, 2012Journal of Bone and Mineral ResearchOpen Access

Incidence and demography of femur fractures with and without atypical features

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To determine the population-level incidence and demographic characteristics of femur fractures with and without atypical features defined by ASBMR criteria.
Conducted a retrospective review of electronic medical records and radiographs from January 1996 to June 2009 at Kaiser Permanente Northwest (1,271,575 person-years observed).
Analyzed 5,034 fractures in women aged ≥50 years and men aged ≥65 years, classifying cases into non-atypical femoral shaft fractures, atypical fracture major features (AFMs), and AFMs with minor features (AFMms).
Incidence rates remained flat over 13.5 years at 18.2 per 100,000 person-years (95% CI, 16.0–20.7) for non-atypical femoral shaft fractures and 5.9 per 100,000 person-years (95% CI, 4.6–7.4) for AFMs.
Prior bisphosphonate exposure was documented in 30.0% of AFM cases compared to 15.8% of non-atypical femoral shaft fractures, with oral glucocorticosteroid dispensing highest in AFM and AFMm groups.
Patients with only major atypical features were older and had lower rates of bisphosphonate dispensing compared to patients exhibiting both major and minor features.

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Implication

Retrospective study observes stable incidence rates of atypical femur fractures in older adults, suggesting true atypia requires both major and minor radiographic features.

Cite This Study

Feldstein et al. (2012) studied this question.

synapsesocial.com/papers/6aa038435a58e1191c2d27b2 https://doi.org/10.1002/jbmr.1550

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Implication

Retrospective study observes stable incidence rates of atypical femur fractures in older adults, suggesting true atypia requires both major and minor radiographic features.

Incidence and demography of femur fractures with and without atypical features

Key Points

Discussion

Implication

Cite This Study

Incidence and demography of femur fractures with and without atypical features

Key Points

Discussion

Implication

Cite This Study

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