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September 28, 2025International Journal of EndocrinologyOpen Access

Biochemical and Demographical Differences in Atypical vs. Typical Femoral Fractures: A 10‐Year Experience Across Two Centers

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Authors

AOAongus O’BrolchainZEZander EnglebrechtRSRichard Steer

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Overview

Retrospective study compares clinical and biochemical profiles of atypical and typical femoral fractures, highlighting distinct diagnostic features.

Key Points

  • Patients with atypical femoral fractures show unique clinical profiles, indicating the need for meticulous management.
  • Among 869 fracture cases, 43 were atypical femoral fractures with significant clinical variances, particularly prior osteoporosis history.
  • Patients with atypical femoral fractures had lower alkaline phosphatase levels, suggesting a distinct biochemical profile during hospitalization.
  • Insights from this analysis may enhance diagnostic accuracy for atypical femoral fractures, urging a reevaluation of ongoing antiresorptive therapy.

Cite This Study

O’Brolchain et al. (2025) studied this question.

synapsesocial.com/papers/68d90bc641e1c178a14f6e09https://doi.org/10.1155/ije/9376426
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