Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 1, 1987Biochemistry and Cell Biology

Attachment of mRNA to the cytoskeletal framework and translational control of gene expression in rat L6 muscle cells

View Full Paper
Ask AI
Bookmark
Share

Key result

In rat L6 muscle cells, binding of mRNA to the cytoskeleton framework and translation of mRNA are two separate events, with a 165-kDa polypeptide preferentially associated with bound mRNA complexes.

Authors

JBJnanankur BagInstitut de Biologie Moléculaire et CellulaireSPSaroj K. PramanikMorgan State University

Discussion

Loading...

Member takes

Implication

No immediate clinical implications for muscle disorders; leaves open the 165-kDa polypeptide's role in human mRNA regulation.

PICO

P
Population
Rat L6 muscle cells
E
Exposure / Comparator
Attachment of mRNA to the cytoskeletal framework

Cite This Study

Bag et al. (1987) studied Rat L6 muscle cells. Attachment of mRNA to the cytoskeletal framework was evaluated. In rat L6 muscle cells, binding of mRNA to the cytoskeleton framework and translation of mRNA are two separate events, with a 165-kDa polypeptide preferentially associated with bound mRNA complexes.

synapsesocial.com/papers/6aa03c1c36ea76a62dc11b37https://doi.org/10.1139/o87-073
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts.1994 · 168 citations
  2. 2Myosin Messenger RNA: Studies on Its Purification, Properties and Translation during Myogenesis in Culture1973 · 48 citations
  3. 3Interaction of proteins with the mRNA for ribosomal protein L1 in<i>Xenopus</i>: structural characterization of<i>in vivo</i>complexes and identification of proteins that bind<i>in vivo</i>to its 5’UTR1993 · 50 citations
  4. 4Cell-free translation of mammalian myosin heavy-chain messenger ribonucleic acid from growing and fused-L6E9 myoblasts1979 · 32 citations
  5. 5Localization of cardiac α-myosin heavy chain mRNA is regulated by its 3′ untranslated region via mechanical activity and translational block1997 · 16 citations