Key result
Women undergoing aortic valve replacement for severe aortic stenosis had similar 5-year survival compared to men (81.4% vs 76.3%; P=0.31), despite older age and more advanced disease.
Why the study?
Does female gender affect operative mortality and long-term survival in patients undergoing aortic valve replacement for isolated severe aortic stenosis?
Population
408 consecutive patients undergoing aortic valve replacement for isolated severe aortic stenosis
Comparison
Female gender vs Male gender
Design
Cohort
Follow-up
5 years
Authors
Loading...
Supports AVR in older women with advanced AS; leaves open gender-specific referral thresholds pending prospective data.
Cohort (n=408)
Does female gender affect operative mortality and long-term survival in patients undergoing aortic valve replacement for isolated severe aortic stenosis?
Absolute Event Rate: 81.4% vs 76.3%
p-value: p=0.31
Despite presenting at an older age and with more advanced disease, women undergoing aortic valve replacement for severe aortic stenosis have similar or better long-term survival compared to men, particularly in those over 79 years old.
Mascherbauer et al. (2010) conducted a cohort in isolated severe aortic stenosis (n=408). Female gender vs. Male gender was evaluated on Survival after AVR at 5 years (p=0.31). Women undergoing aortic valve replacement for severe aortic stenosis had similar 5-year survival compared to men (81.4% vs 76.3%; P=0.31), despite older age and more advanced disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: