July 29, 2014Circulation Cardiovascular Imaging
Tricuspid Regurgitation in Hypoplastic Left Heart Syndrome
Key result
Increased tricuspid valve tethering volume and flatter bending angle prestage 1 palliation in infants with hypoplastic left heart syndrome are associated with tricuspid valve failure and decreased survival.
Why the study?
Does 3-dimensional echocardiography prestage 1 palliation predict tricuspid valve failure and survival in infants with hypoplastic left heart syndrome?
Population
70 infants with hypoplastic left heart syndrome prestage 1 palliation
Design
Cohort
Follow-up
medium-term
Authors
Discussion
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Member takes
Implication
May aid 3D echo risk stratification in HLHS infants; hypothesis-generating pending prospective validation.
Study Design
Type
Cohort (n=70)
Structured PICO
Does 3-dimensional echocardiography prestage 1 palliation predict tricuspid valve failure and survival in infants with hypoplastic left heart syndrome?
P
Population
70 infants with hypoplastic left heart syndrome were prospectively studied with echocardiography prestage 1 palliation and followed for medium-term outcomes.
E
Exposure
3-dimensional echocardiography (3DE) and 2-dimensional echocardiography (2DE)
O
Outcome
Tricuspid regurgitation (TR), tricuspid valve (TV) surgery, transplantation, or deathcomposite
In infants with hypoplastic left heart syndrome, increased tricuspid valve tethering volume and flatter bending angle on 3D echocardiography before stage 1 palliation predict medium-term tricuspid valve failure and reduced survival.
Cite This Study
Kutty et al. (2014) conducted a cohort in Hypoplastic left heart syndrome (n=70). Tricuspid valve abnormalities (increased tethering volume and flatter bending angle) prestage 1 palliation vs. Normal tricuspid valve parameters was evaluated on Tricuspid regurgitation, tricuspid valve surgery, transplantation, or death. Increased tricuspid valve tethering volume and flatter bending angle prestage 1 palliation in infants with hypoplastic left heart syndrome are associated with tricuspid valve failure and decreased survival.