Key result
A diastolic pulmonary vascular pressure gradient (DPG) ≥7 mmHg was associated with increased mortality (HR 2.07), though clinical factors like NT-pro BNP and renal dysfunction were superior predictors.
Authors
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DPG ≥7 mmHg should not yet guide risk stratification; leaves open its incremental value beyond NT-proBNP and renal dysfunction in pulmonary hypertension cohorts.
Cohort (n=243)
No
Hazard Ratio: 2.07 (95% CI 1.07–3.72)
p-value: p=0.031
Yamabe et al. (2015) conducted a cohort in Pulmonary hypertension due to left heart disease (n=243). Diastolic pulmonary vascular pressure gradient (DPG) ≥7 mmHg vs. DPG <7 mmHg was evaluated on All-cause mortality (HR 2.07, 95% CI 1.07-3.72, p=0.031). A diastolic pulmonary vascular pressure gradient (DPG) ≥7 mmHg was associated with increased mortality (HR 2.07), though clinical factors like NT-pro BNP and renal dysfunction were superior predictors.
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