Why the study?
Despite advances in understanding pulmonary hypertension due to left heart failure, mortality remains high, prompting this study to describe prevalence, survival, and prognostic risk factors.
Population
480 patients with LHF undergoing RHC
Comparison
PH-LHF vs without PH-LHF
Design
Retrospective analysis of a multicenter prospective cohort study
Follow-up
Median 84.6 months
Key result
Coronary artery disease was not independently associated with the presence of pulmonary hypertension due to left heart failure (Adjusted OR 1.055; 95% CI 0.576-1.935; P=0.862).
Authors
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CAD does not independently predict PH in left HF; leaves open its role in PH progression or outcomes.
Cohort (n=480)
Yes
Odds Ratio: 1.055 (95% CI 0.576–1.935)
Absolute Event Rate: 41.3% vs 57.8%
p-value: p=0.862
Pulmonary hypertension is present in nearly half of patients with left heart failure undergoing right heart catheterization and is associated with high long-term mortality, which can be predicted by NYHA class, hemoglobin, and systolic pulmonary artery pressure.
Lin et al. (2022) conducted a cohort in Left heart failure (LHF) (n=480). Coronary artery disease (CAD) vs. Without CAD was evaluated on Pulmonary hypertension due to left heart failure (PH-LHF) (Adjusted OR 1.055, 95% CI 0.576-1.935, p=0.862). Coronary artery disease was not independently associated with the presence of pulmonary hypertension due to left heart failure (Adjusted OR 1.055; 95% CI 0.576-1.935; P=0.862).