Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 2014BMJ OpenOpen Access

Pulmonary hypertension is consistently associated with increased mortality risk in all forms of left heart disease, except for aortic valve disease.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does the presence of pulmonary hypertension predict hospitalisations for heart failure and mortality in patients with left heart disease?

Population

45 studies including adults with pulmonary hypertension associated with left heart disease diagnosed via…

Comparison

Presence of pulmonary hypertension and other… vs Absence of pulmonary hypertension or different…

Design

Systematic_review

Key result

Pulmonary hypertension is consistently associated with increased mortality risk in all forms of left heart disease, except for aortic valve disease.

Authors

ADAnastase DzudiéAKAndré Pascal KengneFTFriedrich Thienemann

Discussion

Loading...

Member takes

Overview

Supports incorporating pulmonary hypertension into risk stratification for left heart disease; confirms its consistent prognostic value across most subtypes.

Study Design

Type

Systematic Review

Structured PICO

Does the presence of pulmonary hypertension predict hospitalisations for heart failure and mortality in patients with left heart disease?

P
Population
Systematic review of 45 studies assessing predictors of heart failure hospitalization and mortality in adults with pulmonary hypertension associated with left heart disease.
E
Exposure
Presence of pulmonary hypertension (PH) and other clinical predictors (e.g., right ventricular dysfunction, functional class, left ventricular function, kidney disease)
C
Comparator
Absence of pulmonary hypertension or different baseline predictor levels
O
Outcome
Hospitalisations for heart failure and mortalityhard clinical

Pulmonary hypertension is a consistent predictor of increased mortality and heart failure hospitalisation in patients with left heart disease.

Limitations

  • Effects on hospitalisation risk are yet to be fully characterised
  • Available evidence on the adverse effects of PH have been derived essentially from Caucasians
  • Available evidence derived essentially from Caucasians

Cite This Study

Dzudié et al. (2014) conducted a systematic review in Pulmonary hypertension associated with left heart disease. Pulmonary hypertension was evaluated on Hospitalisations for heart failure and mortality. Pulmonary hypertension is consistently associated with increased mortality risk in all forms of left heart disease, except for aortic valve disease.

synapsesocial.com/papers/6a79e51d684c0941cf3225b7https://doi.org/10.1136/bmjopen-2014-004843
View Full Paper
Ask AI
Bookmark
Share