Key result
Acute necrotizing encephalopathy in pediatric patients with a history of viral infections leads to devastating neurological sequelae and a mortality rate of approximately 30%.
Case Report
Clinicians should maintain a high index of suspicion for acute necrotizing encephalopathy in pediatric patients presenting with neurologic deficits following viral infections.
Supports heightened suspicion for acute necrotizing encephalopathy after viral illness in children; case reports leave open validation in larger cohorts.
Key Clinical Message: Acute necrotizing encephalopathy leads to devastating neurological sequelae and even death. Clinician should try not to miss this diagnosis especially in the pediatrics whenever there are neurological symptoms due to viral infection. Abstract: Acute necrotizing encephalopathy (ANE) is a rare disease affecting the central nervous system. It leads to devastating neurological sequelae with a mortality rate of approximately 30%. Clinicians should have high suspicion whenever there is neurologic deficit and history of viral infections especially involving upper respiratory tract in the pediatric age group.
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Chipongo et al. (2023) conducted a case report in Acute necrotizing encephalopathy. Acute necrotizing encephalopathy in pediatric patients with a history of viral infections leads to devastating neurological sequelae and a mortality rate of approximately 30%.
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