Key result
Combined immunoglobulin and glucocorticoids yield a good outcome in pediatric acute necrotizing encephalopathy.
Case Report (n=1)
Combined therapy with immunoglobulin and glucocorticoids may lead to a good outcome in children with acute necrotizing encephalopathy.
ANE imaging aids diagnosis in acute encephalopathy; leaves open environmental etiology and targeted therapies.
Acute necrotizing encephalopathy (ANE) is a rare clinical-imaging syndrome with unknown etiology, characterized by acute fulminant severe encephalopathy and brain damage with multifocal symmetry. ANE has no specific clinical symptoms and signs, similar to common encephalitis or encephalopathy symptoms. The characteristic brain imaging examination is diagnostically significant. To date, no specific treatment for ANE is available and the prognosis is poor. Here, we reported a typical case of ANE in a child, and where a good outcome was achieved through combined therapy with immunoglobulin and glucocorticoids.
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Yuan et al. (2018) conducted a case report in Acute necrotizing encephalopathy (n=1). Combined therapy with immunoglobulin and glucocorticoids was evaluated on Clinical outcome. Combined therapy with immunoglobulin and glucocorticoids achieved a good outcome in a child with acute necrotizing encephalopathy.
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