Key result
Pulmonary tumor thrombotic microangiopathy is a rare, rapidly progressive, and often fatal complication of malignancy that presents significant diagnostic difficulties.
Case Report (n=1)
Increased clinical awareness of pulmonary tumor thrombotic microangiopathy is necessary to improve the chances of antemortem diagnosis in patients with malignancy presenting with rapid-onset pulmonary hypertension and right heart failure.
Heightened suspicion may aid antemortem PTTM diagnosis in gastric cancer; case reports leave open validated diagnostic algorithms.
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rapidly progressive pulmonary disease complicated by malignancy. It manifests clinically as respiratory distress with pulmonary hypertension, progressive right sided heart failure, and sudden death. We describe a case of PTTM associated with metastatic gastric carcinoma. This case demonstrates the diagnostic diffi culties in such a rare and rapidly fatal oncological complication. More awareness among clinicians may help make a right diagnosis in the short time available. We also review the literatures to demonstrate the clinical characteristics that might provide clues towards an antemortem diagnosis, and may provide the key in treating PTTM.
No takes yet. Share an insight, caveat, or question.
Chien‐Kuang Chen (2018) conducted a case report in Pulmonary tumor thrombotic microangiopathy (PTTM) associated with metastatic gastric carcinoma (n=1). Pulmonary tumor thrombotic microangiopathy is a rare, rapidly progressive, and often fatal complication of malignancy that presents significant diagnostic difficulties.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: