Key result
Aggressive treatment with immunoglobulins and anticholinergics normalized cardiac function in a 70-year-old female with myasthenic crisis-associated reverse takotsubo cardiomyopathy.
Why the study?
Myasthenic crisis is rarely associated with takotsubo cardiomyopathy, and embolic complications of myasthenic crisis-associated reverse takotsubo cardiomyopathy were yet to be documented.
Case Report (n=1)
Highlights the rare association of myasthenic crisis with reverse takotsubo cardiomyopathy and embolic complications, emphasizing the reversibility of cardiac function with appropriate medical care.
Embolic stroke may complicate MC-associated reverse TTC; first report leaves open need for embolic prophylaxis.
Myasthenic crisis (MC) is rarely associated with takotsubo cardiomyopathy (TTC), but embolic complications of MC-associated reverse TTC are yet to be documented. We present a case of a 70-year-old Caucasian female with MC-associated reverse TTC, developing acute cerebral infarcts. Following aggressive treatment with immunoglobulins and anticholinergics, cardiac function normalised. TTC is an important differential diagnosis in acute deteriorations of cardiac function, particularly in intensive care, not only due to frequent use of inotropes and embolic complications but also because cardiac function is reversible with good medical care. Early specialist neurologist and cardiologist input should be sought in such cases.
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Youssef et al. (2022) conducted a case report in Myasthenic crisis-associated reverse takotsubo cardiomyopathy (n=1). Immunoglobulins and anticholinergics was evaluated on Cardiac function normalization. Aggressive treatment with immunoglobulins and anticholinergics normalized cardiac function in a 70-year-old female with myasthenic crisis-associated reverse takotsubo cardiomyopathy.
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