Key result
Rhinovirus isolation shows no conclusive link to lower respiratory disease in infants and children.
Why the study?
Is rhinovirus a significant etiologic agent in children with severe lower respiratory disease requiring hospitalization?
Population
16 infants and children with acute lower respiratory disease associated with rhinovirus isolation
Design
Case_series
Authors
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Rhinovirus isolation in pediatric lower respiratory disease should not imply causation; leaves open its etiologic role pending larger controlled studies.
Observational (n=16)
Is rhinovirus a significant etiologic agent in children with severe lower respiratory disease requiring hospitalization?
Rhinovirus does not appear to be a significant primary etiologic agent for severe lower respiratory disease requiring hospitalization in children.
Portnoy et al. (1965) conducted an observational in Acute lower respiratory disease (n=16). Rhinovirus infection vs. Children without lower respiratory disease was evaluated on Etiological importance in lower respiratory disease. In 16 cases of lower respiratory disease in infants and children, rhinovirus isolation was as frequent as in children without the disease, showing no conclusive evidence of etiological importance.
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