Key result
Pediatric SAN dysfunction is linked to ~48 msec longer SACT versus normal controls.
Why the study?
Does the premature atrial stimulus technique identify abnormal sinoatrial conduction in children with suspected or at-risk sinoatrial node dysfunction compared to normal children?
Population
50 children, including 20 normal children, 20 with documented sinoatrial node dysfunction, and 10 at risk…
Comparison
Premature atrial stimulus technique to measure… vs Normal children without SAN dysfunction
Design
Cross-sectional
Authors
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Prolonged SACT may flag conduction defects when CSNRT is normal; leaves open its added diagnostic value in at-risk children.
Observational (n=50)
Does the premature atrial stimulus technique identify abnormal sinoatrial conduction in children with suspected or at-risk sinoatrial node dysfunction compared to normal children?
Absolute Event Rate: 172% vs 124%
p-value: p=<0.001
The premature atrial stimulus technique effectively measures sinoatrial conduction time in children and identifies abnormalities in those with suspected sinoatrial node dysfunction, even when corrected sinus node recovery time is normal.
Kugler et al. (1979) conducted an observational in Sinoatrial node dysfunction (n=50). Documented sinoatrial node dysfunction vs. Normal sinoatrial node function was evaluated on Total sinoatrial conduction time (SACT) (p=<0.001). Children with documented sinoatrial node dysfunction had significantly prolonged mean total sinoatrial conduction time compared to normal children (172 vs 124 msec; P<0.001).
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