Key result
Mild encephalopathy presents with reversible splenium and frontal white matter MRI lesions resolving within a week.
Population
A 59-year-old man with sudden onset of severe dysarthria and drowsy mental status, diagnosed with mild…
Design
Case_report
Follow-up
1 month
Authors
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Reversible lesions may extend beyond the splenium in mild encephalopathy; extends the phenotype but leaves open generalizability and management impact.
Case Report (n=1)
No
This case report demonstrates that reversible lesions associated with mild encephalopathy can occur outside the splenium of the corpus callosum, specifically in the bilateral frontal white matter.
Cho et al. (2007) conducted a case report in Mild encephalopathy with reversible lesion in the splenium of the corpus callosum and bilateral frontal white matter (n=1). Conservative management was evaluated on Clinical and radiological resolution. A 59-year-old man with mild encephalopathy exhibited reversible MRI lesions in the splenium of the corpus callosum and bilateral frontal white matter that completely resolved within a week.