Key result
Greek EMCV isolate causes more severe fetal pathogenicity than Belgian isolate in gestating sows.
Why the study?
Does the Greek EMCV isolate cause more severe fetal pathogenicity compared to the Belgian isolate in gestating sows?
Population
13 conventional sows between 61 and 92 days of gestation
Comparison
Inoculation with a Greek Encephalomyocarditis… vs Inoculation with a Belgian Encephalomyocarditis…
Design
Preclinical
Authors
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Greek EMCV isolate showed greater fetal pathogenicity in sows; leaves open strain surveillance needs and translational relevance to other species.
Does the Greek EMCV isolate cause more severe fetal pathogenicity compared to the Belgian isolate in gestating sows?
In a sow model, the Greek EMCV isolate caused more severe fetal pathogenicity than the Belgian isolate, though neither caused myocardial lesions.
Koenen et al. (1997) studied Encephalomyocarditis Virus (EMCV) infection (n=13). Greek EMCV isolate vs. Belgian EMCV isolate was evaluated on Transplacental virus transmission and fetal pathogenicity. Inoculation of gestating sows with a Greek EMCV isolate caused more severe fetal pathogenicity than a Belgian isolate, though both caused transplacental virus transmission and fetal death.
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