Key result
CKD and comorbidity are linked to higher all-cause mortality in older adults with pacemakers.
Why the study?
Does chronic kidney disease negatively impact survival in older adults treated with pacemaker implantation for bradyarrhythmias?
Observational (n=538)
Does chronic kidney disease negatively impact survival in older adults treated with pacemaker implantation for bradyarrhythmias?
Answers are grounded in this paper and cite their sources.
Renal dysfunction and comorbidities are significant predictors of mortality in older adults undergoing pacemaker implantation for bradyarrhythmias.
OBJECTIVE: To investigate whether chronic kidney disease could negatively impact survival in older adults needing pacemaker implantation after admission for bradyarrhythmias. METHODS: This retrospective observational study considered 538 older adults consecutively admitted, who had been followed-up for 31 ± 20 months. Subjects with poor short-term prognosis were excluded. Charlson comorbidity index (CCI) and estimated glomerular filtration rate (eGFR) was calculated, along with the independent relationship between all-cause mortality and clinical data. Hazard Ratio (HR) was calculated by Cox regression analysis. CONCLUSIONS: Renal dysfunction, as well as comorbidity, impacts negatively survival of older adults treated with pacemaker implantation because of bradyarrhythmias.
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Fabbian et al. (2017) conducted an observational in Bradyarrhythmias needing pacemaker implantation (n=538). Chronic kidney disease was evaluated on All-cause mortality (p=0.033). Chronic kidney disease and comorbidity were significant predictors of all-cause mortality in older adults treated with pacemaker implantation for bradyarrhythmias.
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