Key result
Deep sedation achieved complete resolution of VT/VF in 80% (12 of 15) of patients with malignant ventricular arrhythmias refractory to usual treatment.
Why the study?
Autonomic nervous system activity influences ventricular tachycardia threshold, and deep sedation may be useful for treating refractory ventricular arrhythmia emergencies.
Does deep sedation and intubation resolve ventricular arrhythmias in conscious patients with refractory VT/VF storm or incessant VT?
Population
46 conscious patients admitted to an ICU for recurrent monomorphic VT, polymorphic VT, or VF
Comparison
Deep sedation and intubation vs usual care alone
Design
Single-center retrospective observational study
Follow-up
Mean 3.7 years
Authors
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May support deep sedation in refractory VT/VF; hypothesis-generating and requires randomized confirmation before practice change.
Observational (n=46)
No
Does deep sedation and intubation resolve ventricular arrhythmias in conscious patients with refractory VT/VF storm or incessant VT?
Deep sedation and intubation serves as an effective and safe temporary bridge to definitive treatment for patients with refractory ventricular arrhythmia storm.
Bundgaard et al. (2020) conducted an observational in Ventricular arrhythmia storm (n=46). Deep sedation was evaluated on Complete resolution of VT/VF. Deep sedation achieved complete resolution of VT/VF in 80% (12 of 15) of patients with malignant ventricular arrhythmias refractory to usual treatment.
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