Key result
Starr-Edwards aortic valve replacement resolves cardiac failure in 4 patients.
Why the study?
Does aortic valve replacement with a Starr-Edwards ball-valve prosthesis improve symptoms and hemodynamics in patients with severe cardiac failure from aortic stenosis and insufficiency?
Case Report (n=4)
Does aortic valve replacement with a Starr-Edwards ball-valve prosthesis improve symptoms and hemodynamics in patients with severe cardiac failure from aortic stenosis and insufficiency?
Aortic valve replacement with a Starr-Edwards prosthesis can successfully resolve severe cardiac failure and improve hemodynamics in patients with aortic valve disease.
Answers are grounded in this paper and cite their sources.
May support valve replacement in severe aortic failure; leaves open durability and generalizability pending controlled trials.
Four patients (ages 54, 59, 59, 62) with severe cardiac failure from aortic stenosis and insufficiency have been successfully operated upon. In each patient the diseased aortic valve was replaced with a Starr-Edwards ball-valve prosthesis. An impressive resolution of the cardiac failure promptly occurred; the left ventricular diastolic pressure in two patients decreased in the operating room from 40 to 10 mm Hg. Subsequently all four patients maintained an adequate cardiac output during their postoperative convalescence. One died from endocarditis three months after operation; the other three are asymptomatic three to nine months following operation.
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Spencer et al. (1964) conducted a case report in Severe cardiac failure from aortic stenosis and insufficiency (n=4). Aortic valve replacement with a Starr-Edwards ball-valve prosthesis was evaluated on Resolution of cardiac failure and survival. Aortic valve replacement with a Starr-Edwards ball-valve prosthesis resulted in prompt resolution of cardiac failure in 4 patients, with 3 remaining asymptomatic at 3 to 9 months post-operation.
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