Key result
Early ECMO support and urgent heart transplantation were successfully performed as a lifesaving strategy in a child with familial cardiomyopathy and H1N1-induced cardiogenic shock.
Case Report (n=1)
Early ECMO support and urgent heart transplantation can be lifesaving and safely performed in pediatric patients with infection-induced myocardial decompensation, even with recent H1N1 infection and heparin-induced thrombocytopenia.
Supports feasibility in refractory pediatric cases; leaves open generalizability and optimal timing pending prospective data.
We report a case of a child with familial cardiomyopathy who contracted H1N1 influenza followed by cardiovascular collapse requiring immediate arteriovenous ECMO support. Despite the lack of experience with heart transplantation (HTx) soon after H1N1 infection, HTx was considered as an exit strategy since restoration of cardiac function was considered unlikely. In contrast to the most common indication for ECMO use in patients with H1N1 infection, early ECMO support in cases with infection-induced myocardial decompensation may be lifesaving. Additionally, this report shows that urgent heart transplantation in a patient on ECMO support can be performed safely after recent H1N1 infection and simultaneous heparin-induced thrombocytopenia, which has not been reported before. This case also indicates that H1N1 vaccination should be considered for potential transplantation candidates to prevent severe infection.
No takes yet. Share an insight, caveat, or question.
Skhirtladze et al. (2011) conducted a case report in Familial cardiomyopathy with H1N1 influenza-induced cardiogenic shock (n=1). ECMO support and urgent heart transplantation was evaluated. Early ECMO support and urgent heart transplantation were successfully performed as a lifesaving strategy in a child with familial cardiomyopathy and H1N1-induced cardiogenic shock.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: