Key result
ViV TAVR with aggressive post-dilation improves mean aortic valve gradients in 5 failed surgical bioprostheses.
Why the study?
Does valve-in-valve transcatheter aortic valve replacement (ViV TAVR) with aggressive post-dilation improve hemodynamics in patients with degenerated 19 mm surgical bioprosthetic valves?
Case Report (n=5)
Does valve-in-valve transcatheter aortic valve replacement (ViV TAVR) with aggressive post-dilation improve hemodynamics in patients with degenerated 19 mm surgical bioprosthetic valves?
Valve-in-valve TAVR with aggressive post-dilation is feasible and yields good hemodynamic outcomes in high-risk patients with degenerated 19 mm surgical bioprostheses.
OBJECTIVE: To demonstrate the feasibility of achieving good hemodynamic results with valve-in-valve transcatheter aortic valve replacement (ViV TAVR) for degenerated 19 mm surgical bioprosthetic valves. BACKGROUND: Considerable controversy exists regarding ViV TAVR within 19mm surgical prostheses due to concerns of elevated valve gradients and mortality. METHODS: Among all patient undergoing ViV TAVR between 7/2016 and 4/2017 for symptomatic severe bioprosthetic aortic stenosis (AS), five had a 19 mm surgical valve in place and were included in this publication. None of the patients had patient-prosthesis mismatch. Aggressive post-dilation was performed in four out of five cases using a special technique we describe below. RESULTS: In all cases, mean aortic valve (AV) gradients significantly improved post-ViV TAVR, particularly after post-dilation. Interestingly, high pressure post-dilation of the ViV resulted in an increase in the diameter of surgical valve stent frame dimensions in nearly all patients who underwent post-dilation. CONCLUSIONS: Good hemodynamic outcome is possible with aggressive post-dilation in patients with 19 mm failed surgical bioprostheses. High-risk patients with 19 mm failed surgical prostheses who do not otherwise have viable surgical options should be considered for ViV TAVR.
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Patel et al. (2017) conducted a case report in Symptomatic severe bioprosthetic aortic stenosis (n=5). Valve-in-valve transcatheter aortic valve replacement (ViV TAVR) with aggressive post-dilation was evaluated on Mean aortic valve (AV) gradients. Valve-in-valve transcatheter aortic valve replacement with aggressive post-dilation improved mean aortic valve gradients in all 5 cases with 19 mm failed surgical bioprostheses.
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