Key result
Pericardiectomy resolves a case of constrictive pericarditis linked to the second BNT162b2 vaccine dose.
Why the study?
Constrictive pericarditis is a rare but severe complication following mRNA-based SARS-CoV-2 vaccination presenting with symptoms of right ventricular failure.
Case Report (n=1)
Highlights a rare case of constrictive pericarditis requiring pericardiectomy following mRNA SARS-CoV-2 vaccination.
Answers are grounded in this paper and cite their sources.
Should not change vaccination practice; leaves open whether mRNA vaccines can rarely cause surgically managed constrictive pericarditis.
Constrictive pericarditis is quite rare complication of messenger ribonucleic acid-based severe acute respiratory syndrome-Coronavirus 2 (SARS-CoV-2) vaccine. It is a severe clinical picture with clinical symptoms of right ventricular failure. Initial physical examination, laboratory work-up, and chest X-ray may yield non-specific findings. Echocardiography, computed tomography, and cardiac catheterization are other diagnostic tools. Surgery with pericardiectomy is the definitive treatment option. Herein, we report a case of pericardiectomy after constrictive pericarditis associated with the second dose of BNT162b2 vaccine.
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Demirtaş et al. (2024) conducted a case report in Constrictive pericarditis associated with BNT162b2 vaccine (n=1). Pericardiectomy was evaluated. Pericardiectomy was performed as a definitive treatment for a case of constrictive pericarditis associated with the second dose of the BNT162b2 vaccine.
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