Why the study?
The suitability of pulmonary artery banding as a treatment strategy for dilated cardiomyopathy and left ventricular non-compaction cardiomyopathy with depressed left ventricular ejection fraction needed to be assessed.
Does pulmonary artery banding combined with medical therapy improve left ventricular ejection fraction in patients with dilated or non-compaction cardiomyopathy with LVEF <35%?
Population
21 patients with dilated cardiomyopathy or left ventricular non-compaction cardiomyopathy and LVEF less than 35%
Comparison
Pulmonary artery banding plus anti-congestion medication vs anti-congestion medication alone
Design
Retrospective study
Follow-up
5 years
Key result
Pulmonary artery banding significantly improved left ventricular ejection fraction over 5 years compared to anti-congestion medication alone in pediatric patients with dilated or non-compaction cardiomyopathy (p=0.0002).
Authors
Loading...
Pulmonary artery banding may improve LVEF in select pediatric DCM/LVNC cases; leaves open its role pending larger prospective studies.
Cohort (n=21)
No
Does pulmonary artery banding combined with medical therapy improve left ventricular ejection fraction in patients with dilated or non-compaction cardiomyopathy with LVEF <35%?
p-value: p=0.0002
Pulmonary artery banding combined with anti-congestion medication significantly improves left ventricular ejection fraction and cardiac restoration indices in patients with dilated and non-compaction cardiomyopathy compared to medical therapy alone.
Semyashkin et al. (2025) conducted a cohort in Dilated cardiomyopathy or left ventricular non-compaction cardiomyopathy with depressed LVEF (n=21). Pulmonary artery banding vs. Anti-congestion medication alone was evaluated on Left ventricular ejection fraction (LVEF) (p=0.0002). Pulmonary artery banding significantly improved left ventricular ejection fraction over 5 years compared to anti-congestion medication alone in pediatric patients with dilated or non-compaction cardiomyopathy (p=0.0002).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: