Key result
High-grade pleomorphic sarcoma causing LVOT obstruction results in sudden death at 5 months despite chemotherapy.
Case Report (n=1)
Highlights a rare case of metastatic high-grade pleomorphic sarcoma causing left ventricular outflow tract obstruction and sudden cardiac death.
Alerts clinicians to sudden death risk in rare cardiac sarcoma metastases; leaves open optimal surveillance and therapy strategies.
We present a patient with cardiac involvement by a metastatic high-grade pleomorphic sarcoma. The tumor metastasized to the endocardium of the left ventricle as well as the lungs, adrenal glands, and thoracolumbar spine. The sarcoma obstructed the left ventricular outflow tract. Approximately 5 months after diagnosis, despite chemotherapy, our patient died suddenly. The exact cause of death is unknown, but presumably cardiac in origin
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Stephen D. Clements (2015) conducted a case report in Metastatic high-grade pleomorphic sarcoma with cardiac involvement (n=1). Chemotherapy was evaluated on Death. A patient with metastatic high-grade pleomorphic sarcoma causing left ventricular outflow tract obstruction died suddenly 5 months after diagnosis despite chemotherapy.
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