Key result
Takotsubo syndrome develops in a heart transplant recipient despite absent functional sympathetic reinnervation.
Case Report (n=1)
This case demonstrates that Takotsubo syndrome can occur in heart transplant recipients even in the absence of functional sympathetic nerve system reconstruction.
Takotsubo syndrome can occur without sympathetic reinnervation in transplant recipients; leaves open non-neural mechanisms and requires prospective study.
Takotsubo syndrome (TTS), also referred to as stress cardiomyopathy, is characterized by transient left ventricular apical ballooning in the absence of obstructive coronary artery disease. Catecholamine-induced cardiac injury or vasospasm has been implicated in this pathophysiology. We present a case of a 67-year-old man 10 years after heart transplantation diagnosed with TTS. Sympathetic reinnervation could not be detected by iodine-123 meta iodobenzylguanidine uptake, suggesting that TTS can occur in the absence of functional sympathetic nerve systems reconstruction.
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Miyake et al. (2020) conducted a case report in Takotsubo syndrome (n=1). Heart transplantation was evaluated on Detection of sympathetic reinnervation by iodine-123 meta iodobenzylguanidine uptake. Takotsubo syndrome occurred in a 67-year-old heart transplant recipient despite the absence of functional sympathetic nerve system reconstruction.
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