Key result
Patients with failed antitachycardia pacing had a significantly longer local activation time expressed as a proportion of ventricular tachycardia cycle length compared to those with successful pacing (0.40 vs 0.19; P=0.012).
Why the study?
Is delayed local activation time derived from stored EGM associated with failure of antitachycardia pacing in patients with implantable defibrillators?
Population
Patients with implantable cardioverter defibrillators experiencing ventricular tachycardia
Comparison
Delayed local activation time derived from… vs Shorter local activation time
Design
Case-control
Authors
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May predict ATP failure from stored EGMs; hypothesis-generating and should not change practice without prospective validation.
Case-Control
Is delayed local activation time derived from stored EGM associated with failure of antitachycardia pacing in patients with implantable defibrillators?
Absolute Event Rate: 0.4% vs 0.19%
p-value: p=0.012
Delayed local activation time derived from stored ICD electrograms is associated with the failure of antitachycardia pacing to terminate ventricular tachycardia.
Lim et al. (2009) conducted a case-control in Ventricular tachycardia in patients with implantable defibrillators. Failed antitachycardia pacing (ATP) vs. Successful ATP was evaluated on Local activation time expressed as a proportion of VT cycle length (p=0.012). Patients with failed antitachycardia pacing had a significantly longer local activation time expressed as a proportion of ventricular tachycardia cycle length compared to those with successful pacing (0.40 vs 0.19; P=0.012).
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