Why the study?
Is there a relation between the course of depression and CRP concentrations after an acute coronary syndrome event?
Observational
Is there a relation between the course of depression and CRP concentrations after an acute coronary syndrome event?
This study aims to investigate the relationship between depression remission and inflammatory biomarkers (CRP) following an acute coronary syndrome to better understand the depression-ACS prognosis link.
Association between post-ACS depression course and CRP remains unquantified; leaves open inflammation's role in prognosis.
A lthough depression symptoms are associated with an increased risk of recurrent cardiovascular disease in patients who have experienced an acute coronary syndrome (ACS) event, the exact mechanisms remain poorly understood.Inflammation has been suggested to be a mechanism in the depression-ACS prognosis link, as raised concentrations of inflammatory biomarkers, especially C reactive protein (CRP), are associated with recurrent cardiovascular events. 1 In the few studies that have examined the relation between depression status and CRP concentrations after an ACS event, depression and CRP concentrations were assessed 2-6 months after the index ACS event, when the rate of depression remission would already be relatively high.[2][3][4] The objective of this study was to examine the relation between the course of depression and CRP concentrations after an ACS event.
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Daichi Shimbo (2006) conducted an observational in Acute coronary syndrome and depression. Course of depression was evaluated on C reactive protein (CRP) concentrations.
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